Dexmedetomidine - Revision history

Cmclendon: Added some details

2022-08-09T15:41:53Z

Added some details

← Older revision		Revision as of 08:41, 9 August 2022
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	~~Provide a brief summary of this drug here~~.		Dexmedetomidine is an alpha-2 agonist that has been shown to have analgesic, anxiolytic, and sedative properties<ref name=":0">{{Cite journal\|last=DiLorenzo\|first=Amy N.\|last2=Schell\|first2=Randall M.\|date=2014-08\|title=Morgan & Mikhail’s Clinical Anesthesiology, 5th Edition\|url=http://dx.doi.org/10.1213/ane.0000000000000298\|journal=Anesthesia & Analgesia\|volume=119\|issue=2\|pages=495–496\|doi=10.1213/ane.0000000000000298\|issn=0003-2999}}</ref>.

	== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==		== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==
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	===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===		===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===

	===Precautions<!-- List precautions for use of the drug. If none, this section may be removed. -->~~===~~		===Precautions===
			Should be used with caution with any drugs that lower heart rate or cause hypotension as it may contribute to these hemodynamic changes.<ref name=":0" /> <!-- List precautions for use of the drug. If none, this section may be removed. -->

	==Pharmacology==		==Pharmacology==

Huckfinne: add minor bits for MOA.

2022-07-18T17:50:21Z

add minor bits for MOA.

← Older revision		Revision as of 10:50, 18 July 2022
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	====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====		====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====
	~~alpha~~-2 agonist		Central α-2 agonist with a 1600:1 affinity for α-2 receptors over α-1 receptors.

	====Adverse effects<!-- Describe any potential adverse effects of the drug. -->====		====Adverse effects<!-- Describe any potential adverse effects of the drug. -->====

Chris.Rishel: Added embedded dosage calculation

2022-03-30T07:10:54Z

Added embedded dosage calculation

← Older revision		Revision as of 00:10, 30 March 2022
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	\| routes = IV, IM, IN		\| routes = IV, IM, IN
	\| dosage =		\| dosage =
			\| dosage_calculation = dexmedetomidine
	\| mechanism = Alpha-2 agonism		\| mechanism = Alpha-2 agonism
	\| adverse_effects =		\| adverse_effects =

Rodonnell at 04:29, 4 February 2022

2022-02-04T04:29:39Z

← Older revision		Revision as of 21:29, 3 February 2022
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	== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==		== Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. --> ==
			ICU, intra-operative, and procedural sedation without respiratory depression or amnestic properties. May decrease opioid requirement, more so due to sedating rather than analgesic effects.

	== Contraindications<!-- List contraindications and precautions for use of the drug. --> ==		==Contraindications<!-- List contraindications and precautions for use of the drug. -->==

	=== Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. --> ===		===Absolute contraindications<!-- List absolute contraindications for use of the drug. If none, this section may be removed. -->===

	=== Precautions<!-- List precautions for use of the drug. If none, this section may be removed. --> ===		===Precautions<!-- List precautions for use of the drug. If none, this section may be removed. -->===

	== Pharmacology ==		==Pharmacology==

	=== Pharmacodynamics<!-- Describe the effects of the drug on the body. If appropriate, add subsections by organ system --> ===		===Pharmacodynamics<!-- Describe the effects of the drug on the body. If appropriate, add subsections by organ system -->===

	==== Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. --> ====		====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====
	alpha-2 agonist		alpha-2 agonist

	==== Adverse effects<!-- Describe any potential adverse effects of the drug. --> ====		====Adverse effects<!-- Describe any potential adverse effects of the drug. -->====
			Risk of hypotension and bradycardia, in a dose-dependent manner. Night terrors and transient behavioral effects in children have been reported when used for pre-anesthetic sedation, due to calming effects without amnestic properties.

	=== Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. --> ===		===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===

	== Chemistry and formulation<!-- Describe the chemistry and formulation of the drug. --> ==		==Chemistry and formulation<!-- Describe the chemistry and formulation of the drug. -->==

	== History<!-- Describe the historical development of the drug. --> ==		==History<!-- Describe the historical development of the drug. -->==

	== References ==		==References==

	[[Category:Drug reference]]		[[Category:Drug reference]]
	[[Category:Sedative hypnotics]]		[[Category:Sedative hypnotics]]

Chris.Rishel at 11:27, 12 November 2021

2021-11-12T11:27:31Z

← Older revision		Revision as of 04:27, 12 November 2021
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	[[Category:Drug reference]]		[[Category:Drug reference]]
			[[Category:Sedative hypnotics]]

Chris.Rishel at 11:06, 12 November 2021

2021-11-12T11:06:45Z

← Older revision		Revision as of 04:06, 12 November 2021
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	{{Infobox drug reference		{{Infobox drug reference
	\| trade_names =		\| trade_names =
			\| image_file = Dexmedetomidine.svg
	\| drug_class = Sedative hypnotic		\| drug_class = Sedative hypnotic
	\| drug_class_color = sedative_hypnotic		\| drug_class_color = sedative_hypnotic

Chris.Rishel at 11:06, 12 November 2021

2021-11-12T11:06:24Z

← Older revision		Revision as of 04:06, 12 November 2021
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	{{Infobox drug reference		{{Infobox drug reference
	\| trade_names =		\| trade_names =
	\| drug_class =		\| drug_class = Sedative hypnotic
	\| drug_class_color =		\| drug_class_color = sedative_hypnotic
	\| uses =		\| uses =
	\| contraindications =		\| contraindications =
	\| routes =		\| routes = IV, IM, IN
	\| dosage =		\| dosage =
			\| mechanism = Alpha-2 agonism
			\| adverse_effects =
			\| time_onset =
			\| duration =
			\| metabolism =
			\| halflife_redistribution =
			\| halflife_elimination =
			\| clearance =
			\| protein_binding =
	}}		}}

Oliviamsutton: Created page with "{{Infobox drug reference | trade_names = | drug_class = | drug_class_color = | uses = | contraindications = | routes = | dosage = }} Provide a brief summary of this dr..."

2021-11-10T17:21:59Z

Created page with "{{Infobox drug reference | trade_names = | drug_class = | drug_class_color = | uses = | contraindications = | routes = | dosage = }} Provide a brief summary of this dr..."

New page

{{Infobox drug reference
| trade_names =
| drug_class =
| drug_class_color =
| uses =
| contraindications =
| routes =
| dosage =
}}

Provide a brief summary of this drug here.

== Uses ==

== Contraindications ==

=== Absolute contraindications ===

=== Precautions ===

== Pharmacology ==

=== Pharmacodynamics ===

==== Mechanism of action ====
alpha-2 agonist

==== Adverse effects ====

=== Pharmacokinetics ===

== Chemistry and formulation ==

== History ==

== References ==

[[Category:Drug reference]]