Rocuronium - Revision history

Chris.Rishel at 21:27, 22 December 2022

2022-12-22T21:27:36Z

← Older revision		Revision as of 14:27, 22 December 2022
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	\| contraindications =		\| contraindications =
	\| routes = Intravenous		\| routes = Intravenous
	\| dosage = ~~Intravenous~~		\| dosage =
	~~- Standard Intubation Dose: 0.6 mg/kg~~
	~~- Rapid Sequence Intubation Dose: 1.2 mg/kg~~
	~~- Defasciculating Dose: 0.1 mg/kg~~
	\| halflife_redistribution =		\| halflife_redistribution =
	\| protein_binding =		\| protein_binding =

Sydneyjaj: Added basic information on rocuronium mechanism of action and dosing.

2022-12-22T19:56:57Z

Added basic information on rocuronium mechanism of action and dosing.

← Older revision		Revision as of 12:56, 22 December 2022
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	\| contraindications =		\| contraindications =
	\| routes = Intravenous		\| routes = Intravenous
	\| dosage =		\| dosage = Intravenous
			- Standard Intubation Dose: 0.6 mg/kg
			- Rapid Sequence Intubation Dose: 1.2 mg/kg
			- Defasciculating Dose: 0.1 mg/kg
	\| halflife_redistribution =		\| halflife_redistribution =
	\| protein_binding =		\| protein_binding =
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	\| adverse_effects =		\| adverse_effects =
	\| metabolism =		\| metabolism =
	\| duration =		\| duration = 35-75 minutes (Dose Dependent)
	\| time_onset =		\| time_onset = Standard Intubating Dose: 1.5 minutes
			Rapid Sequence Induction Dose: 90 seconds
	\| dosage_calculation = rocuronium		\| dosage_calculation = rocuronium
	\| mechanism = Nicotinic acetylcholine antagonism		\| mechanism = Nicotinic acetylcholine antagonism
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	}}		}}

	~~Provide a brief summary of this drug here~~.
			Rocuronium is an intermediate duration non-depolarizing muscle relaxant.

	==Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. -->==		==Uses<!-- Describe uses of the drug. If appropriate, add subsections for each indication. -->==
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	====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====		====Mechanism of action<!-- Describe the mechanism of action for the primary uses of the drug. -->====
			Rocuronium is a competitive nicotinic acetylcholine receptor antagonist. By blocking acetylcholine from binding it inhibits depolarization.<ref name=":0">{{Citation\|last=Butterworth IV\|first=John F.\|title=Neuromuscular Blocking Agents\|date=2022\|url=http://accessmedicine.mhmedical.com/content.aspx?aid=1190604416\|work=Morgan & Mikhail’s Clinical Anesthesiology\|edition=7\|place=New York, NY\|publisher=McGraw-Hill Education\|access-date=2022-12-22\|last2=Mackey\|first2=David C.\|last3=Wasnick\|first3=John D.}}</ref>

	====Adverse effects<!-- Describe any potential adverse effects of the drug. -->====		====Adverse effects<!-- Describe any potential adverse effects of the drug. -->====

	===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===		===Pharmacokinetics<!-- Describe the pharmacokinetics of the drug. -->===
			Onset for 0.6 - 0.8 mg/kg Dose: 1.5 minutes

			Onset for 0.9 - 1.2 mg/kg Dose: 60 - 90 seconds<ref name=":0" />

	==Chemistry and formulation<!-- Describe the chemistry and formulation of the drug. -->==		==Chemistry and formulation<!-- Describe the chemistry and formulation of the drug. -->==
			Monoquaternary steroid non-depolarizing muscle relaxant.<ref name=":0" />

	==History<!-- Describe the historical development of the drug. -->==		==History<!-- Describe the historical development of the drug. -->==

Chris.Rishel: Added embedded dosage calculation

2022-03-30T07:33:36Z

Added embedded dosage calculation

← Older revision		Revision as of 00:33, 30 March 2022
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	{{Infobox drug reference		{{Infobox drug reference
	\| trade_names =Zemuron		\| trade_names = Zemuron
	\| drug_class =Neuromuscular blocker		\| drug_class = Neuromuscular blocker
	\| drug_class_color =neuromuscular_blocker		\| drug_class_color = neuromuscular_blocker
	\| uses =		\| uses =
	\| contraindications =		\| contraindications =
	\| routes =Intravenous		\| routes = Intravenous
	\| dosage =		\| dosage =
	\|halflife_redistribution=\|protein_binding=\|clearance=\|halflife_elimination=\|adverse_effects=\|metabolism=\|duration=\|time_onset=\|mechanism=Nicotinic acetylcholine antagonism\|image_file=Rocuronium.svg}}		\| halflife_redistribution =
			\| protein_binding =
			\| clearance =
			\| halflife_elimination =
			\| adverse_effects =
			\| metabolism =
			\| duration =
			\| time_onset =
			\| dosage_calculation = rocuronium
			\| mechanism = Nicotinic acetylcholine antagonism
			\| image_file = Rocuronium.svg
			}}

	Provide a brief summary of this drug here.		Provide a brief summary of this drug here.

Chris.Rishel at 11:25, 12 November 2021

2021-11-12T11:25:58Z

← Older revision		Revision as of 04:25, 12 November 2021
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	[[Category:Drug reference]]		[[Category:Drug reference]]
			[[Category:Neuromuscular blockers]]
			[[Category:Nondepolarizing neuromuscular blockers]]

Chris.Rishel: Created page with "{{Infobox drug reference | trade_names =Zemuron | drug_class =Neuromuscular blocker | drug_class_color =neuromuscular_blocker | uses = | contraindications = | routes =Int..."

2021-11-12T11:01:31Z

Created page with "{{Infobox drug reference | trade_names =Zemuron | drug_class =Neuromuscular blocker | drug_class_color =neuromuscular_blocker | uses = | contraindications = | routes =Int..."

New page

{{Infobox drug reference
| trade_names =Zemuron
| drug_class =Neuromuscular blocker
| drug_class_color =neuromuscular_blocker
| uses =
| contraindications =
| routes =Intravenous
| dosage =
|halflife_redistribution=|protein_binding=|clearance=|halflife_elimination=|adverse_effects=|metabolism=|duration=|time_onset=|mechanism=Nicotinic acetylcholine antagonism|image_file=Rocuronium.svg}}

Provide a brief summary of this drug here.

==Uses==

==Contraindications==

===Absolute contraindications===

===Precautions===

==Pharmacology==

===Pharmacodynamics===

====Mechanism of action====

====Adverse effects====

===Pharmacokinetics===

==Chemistry and formulation==

==History==

==References==

[[Category:Drug reference]]